glutathione and diabetes mellitus prevents chronic oscillating glucose intake-induced β-cell dedifferentiation failure Effects of Vitamin E and

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2) The receptor-dependent pathway refers to the direct binding of the LIR motif mitophagy-related receptor to LC3, independent of ubiquitination, and the transport of damaged or redundant mitochondria to autophagosomes to achieve mitochondrial selective autophagic degradation

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Safety therapeutic relevance: Even well-tolerated compounds require strong efficacy signals to justify continued development